Animal Cell Technology(Paperback), 1/e
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Animal Cell Technology(Paperback), 1/e

Author : Asok Mukhopadhyay
© Year : 2013
ISBN : 9789382335664
Pages : 380
Binding : Paperback
Weight : 0.75   kg
Discount : 20.00  %
Price :   65.00      52.00
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  • About the Book
  • Salient Features
  • Table of Contents
  • About the Author

Animal cell technology has made tremendous progress in human healthcare. With the advent of recombinant DNA and hybridization technology it is now possible to manufacture many complex therapeutic proteins using animal cells, which otherwise could not be produced or isolated from natural sources. Another form of products where cells are directly involved is regenerative medicine and tissue engineering. Hence, the future of healthcare relies on the progress on these new endeavors of animal cell technology.
Broadly divided in four sections and sixteen chapters this book is meant for the diverse background of students starting from the basic biology to the bioengineering discipline. Since, animal cell technology commands proper understanding of cell biology, DNA technology, immunology and bioengineering, the goal of this book is to amalgamate knowledge from these fields and pass on to the readers who intend to start professional carrier in academic or in industrial research.
An animal cell is a unique factory, where thousands of genes are encoded and transcribed; products are translated, and finally processed to biologically active molecules. It is therefore, important to understand inside of a cell, how cellular functions are coordinated, limitation of cells, reasons for proliferation and cellular death. The very first section of the book deals with the basic biological aspects to understand cell and how it functions. The second section offers basic cell culture technology among the readers. This section covers preservation of animal cells, cell culture medium, culture environment, good manufacturing practices and equipment, quantitative analysis, etc. In the third section, recombinant therapeutic proteins, large-scale cell culture, and scale-up processes are discussed. The fourth section provides glimpses of the advanced studies, where therapeutic applications of cells and tissues have been discussed. Embryonic and somatic stem cells, cloning, tissue engineering are the main subjects of this section. Finally, in the concluding section the future perspective of animal cell culture technology has been discussed.

Salient Features:

  • Spread across 16 chapters, the subject matter is divided into 4 sections dealing broadly with an introduction to cell biology, basic cell culture technology, therapeutic proteins and bio engineering aspects, and advanced cell culture technology.
  • Aspects of culture, preservation, analysis, therapeutics and real-life applications have been discussed in the book.
  • Pictures and labelled diagrams (many in colour) have been included appropriately.
  • A detailed glossary of important terms is provided at the end of the book.
  • Each chapter ends with a summary, a list of abbreviations used, references, and suggested further readings.

  • Section-I: Introduction to cell biology
  • Organization of animal cells and special properties
  • Proliferation and death of animal cells: Molecular mechanism
  • Sources of animal cells and establishing primary culture. Section-II: Basic cell culture technology
  • Preservation and control of cell lines
  • Design of cell culture medium
  • Good manufacturing practices, aseptic techniques, and cell culture equipment
  • Environmental factors and cell culture methods
  • Separation of viable cells
  • Quantitative analysis. Section-III: Therapeutic proteins and bioengineering aspects
  • Stable gene expression in mammalian cells and monoclonal antibody
  • Large scale animal cell culture for production of therapeutics
  • Scale-up studies in animal cell culture bioreactors. Section-IV: Advanced cell culture technology
  • Embryonic and adult stem cells
  • Cloning and gene therapy
  • Regenerative medicine.

Asok Mukhopadhyay :- Asok Mukhopadhyay is a senior scientist at the National Institute of Immunology, New Delhi. His areas of working are stem cell research, tissue engineering, and therapeutic applications of stem cells. He did Master's in Technology and Doctorate in Philosophy in the field of Biochemical Engineering and Biotechnology from Indian Institute of Technology, Delhi, India. He did Postdoctoral Research from MD Anderson Cancer Center, Houston, Texas, USA.

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