The main purpose of this book is the need to create awareness amongst public in regard to the DNA fingerprinting technology, its applications and implications. This book deals with several applications of DNA fingerprinting, from parental disputes to familial matters, forensics to medicine, smuggling to poaching of animals, man-made to natural disasters, conservation to reproduction, and so on. It contains several cases where DNA-evidence played an important role in arriving at the verdict. Many of these cases from India were referred to the Centre for Cellular and Molecular Biology (CCMB). As far as these cases are concerned, they are representative of various types of disputes; cases of similar nature are reported all around the world. Some of the cases have been chosen because of their historic perspective, high-profile status (social or political) of personalities involved, or because they were publicized internationally. The book illustrates how DNA fingerprinting was crucial under the variety of these circumstances in providing justice to the victim or in unraveling the truth behind ongoing conflicts or confusions.Legal and ethical concerns which have emerged due to the application of DNA fingerprinting have been addressed in the concluding chapters.
1. Historical Background 2. Traditional Methods of Identification 3. Basis of DNA Fingerprinting 4. How is DNA Fingerprinting Done 5. Advances in DNA Fingerprinting Technologies 6. Applications of DNA Fingerprinting 7. Large Scale (High Throughput) Applications of DNA Fingerprinting 8. Typical Cases Solved Using DNA Fingerprinting 9. DNA - Punishes as well as Exonerates 10. DNA Fingerprinting and Legal Issues 11. DNA Fingerprinting and Ethical Issues 12. Future Perspectives References Index
Lalji Singh :- Lalji Singh after obtaining M.Sc. and Ph.D. from Banaras Hindu University, spent about 13 years in the Institute of Animal Genetics, University of Edinburgh (1974-1987) before joining CCMB. Since July 1998, he is the Director at the Centre for Cellular and Molecular Biology (CCMB), Hyderabad. He is internationally known for his contribution in the area of molecular basis of sex determination. As a follow-up of this work, he developed an indigenous probe for DNA fingerprinting. He was responsible for setting-up an autonomous Centre for DNA Fingerprinting and Diagnostics (CDFD) at Hyderabad, which is funded by the DBT, Govt. of India, for which he was the Officer on Special Duty for first three and a half years. Because of his efforts, the evidence based on DNA fingerprinting is now being accepted in the Indian Court of Law. He has been responsible in setting-up of the Laboratory for the Conservation of Endangered SpElectronics\Communication and Instrumentation Engineerings (LaCONES) as a separate campus of CCMB. Madhusudan W Pandit :- Madhusudan W. Pandit obtained his Ph.D. from the University of Pune in 1970. He has worked as a professional Scientist at various institutions such as NCL, Pune; RRL, IICT & CCMB, Hyderabad. After his retirement in 1993, he has worked as a Consultant at NAL, Bangalore. As a Consultant, he helped in establishing the Centre for DNA Fingerprinting and Diagnostics (CDFD), an autonomous centre of the Dept. of Biotechnology, Govt. of India. At present, he is working as a Consultant to the CCMB on the Project “Laboratory for the Conservation of Endangered SpElectronics\Communication and Instrumentation Engineerings (LaCONES)”.
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